Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:9759
  • Symbol:HDAC4
  • Description:histone deacetylase 4

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9759 GO:0000118 IDA part_of histone deacetylase complex 11804585 Component
9759 GO:0000785 IDA part_of chromatin 31127039 Component
9759 GO:0005634 IDA located_in nucleus 10869435,19281832,23867755,26019235 Component
9759 GO:0005654 IDA located_in nucleoplasm Component
9759 GO:0005737 IDA located_in cytoplasm 10869435,19281832 Component
9759 GO:0005829 IDA located_in cytosol Component
9759 GO:0016607 IDA located_in nuclear speck Component
9759 GO:0017053 IDA part_of transcription repressor complex 11804585 Component

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9759 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 16236793 Process
9759 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 10869435 Process
9759 GO:0000122 IGI acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 15743821 Process
9759 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 18850004,19276356 Process
9759 GO:0006338 IDA involved_in chromatin remodeling 18850004 Process
9759 GO:0006476 IDA involved_in protein deacetylation 27708256 Process
9759 GO:0008284 IMP involved_in positive regulation of cell population proliferation 18850004 Process
9759 GO:0010832 IMP involved_in negative regulation of myotube differentiation 10983972 Process
9759 GO:0016575 IDA involved_in histone deacetylation 10869435 Process
9759 GO:0016575 IMP involved_in histone deacetylation 18850004 Process
9759 GO:0033235 IDA involved_in positive regulation of protein sumoylation 17696781 Process
9759 GO:0034983 IDA involved_in peptidyl-lysine deacetylation 18614528 Process
9759 GO:0040029 IMP involved_in epigenetic regulation of gene expression 24413532 Process
9759 GO:0043393 IMP involved_in regulation of protein binding 19071119 Process
9759 GO:0043433 IMP involved_in negative regulation of DNA-binding transcription factor activity 18850004 Process
9759 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 10869435 Process
9759 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 19276356 Process
9759 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 19071119 Process
9759 GO:0051091 IMP involved_in positive regulation of DNA-binding transcription factor activity 19071119 Process
9759 GO:0060337 IDA involved_in type I interferon-mediated signaling pathway 31127039 Process
9759 GO:0070555 IMP involved_in response to interleukin-1 19281832 Process
9759 GO:0070932 IDA involved_in histone H3 deacetylation 12590135 Process
9759 GO:0070933 IDA involved_in histone H4 deacetylation 12590135 Process

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9759 GO:0000976 IDA contributes_to transcription cis-regulatory region binding 18850004 Function
9759 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 24413532 Function
9759 GO:0004407 IDA enables histone deacetylase activity 10220385,10869435 Function
9759 GO:0005515 IPI enables protein binding 10869435,10958686,11463856,11504882,11804585,15161933,15194749..... Function
9759 GO:0008270 IDA enables zinc ion binding 18614528 Function
9759 GO:0019789 EXP enables SUMO transferase activity 17218271 Function
9759 GO:0030955 IDA enables potassium ion binding 18614528 Function
9759 GO:0033558 IDA enables protein lysine deacetylase activity 18614528 Function
9759 GO:0042802 IPI enables identical protein binding 17360518 Function
9759 GO:0042826 IPI enables histone deacetylase binding 10869435,12590135 Function
9759 GO:0043565 IDA contributes_to sequence-specific DNA binding 19276356 Function
9759 GO:0060090 IDA enables molecular adaptor activity 31127039 Function
9759 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 18850004,19071119,23867755 Function
9759 GO:0140297 IPI enables DNA-binding transcription factor binding 10983972,11804585 Function