Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:983
  • Symbol:CDK1
  • Description:cyclin dependent kinase 1

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
983 GO:0000307 IDA part_of cyclin-dependent protein kinase holoenzyme complex 1312467 Component
983 GO:0000781 HDA located_in chromosome, telomeric region 19135898 Component
983 GO:0005634 IDA located_in nucleus 15767402,16109376 Component
983 GO:0005654 IDA located_in nucleoplasm Component
983 GO:0005737 IDA located_in cytoplasm 15767402 Component
983 GO:0005759 IDA colocalizes_with mitochondrial matrix 24746669 Component
983 GO:0005813 IDA located_in centrosome 17488717 Component
983 GO:0005829 IDA located_in cytosol Component
983 GO:0005876 IDA located_in spindle microtubule 11069302 Component
983 GO:0016020 HDA located_in membrane 19946888 Component
983 GO:0030496 IDA located_in midbody 11069302 Component
983 GO:0070062 HDA located_in extracellular exosome 19056867 Component
983 GO:0072686 IDA located_in mitotic spindle 17488717 Component
983 GO:0097125 IMP part_of cyclin B1-CDK1 complex 24746669 Component
983 GO:0097125 IPI part_of cyclin B1-CDK1 complex 17495531 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
983 GO:0004672 IDA enables protein kinase activity 22854038,23574715 Function
983 GO:0004674 IDA enables protein serine/threonine kinase activity 7588608,11298763,19879842,21871177,23509069,26829474,27030108..... Function
983 GO:0004693 IDA enables cyclin-dependent protein serine/threonine kinase activity 10791892,11069302,18477460,23601106,25753036,34734636..... Function
983 GO:0004693 IMP enables cyclin-dependent protein serine/threonine kinase activity 24746669 Function
983 GO:0005515 IPI enables protein binding 7815540,9001210,9988268,10373560,11069302,11574543,11687586,12..... Function
983 GO:0008353 IDA enables RNA polymerase II CTD heptapeptide repeat kinase activity 12721286 Function
983 GO:0016301 IDA enables kinase activity 28575661 Function
983 GO:0030332 IDA enables cyclin binding 7739547 Function
983 GO:0030332 IPI enables cyclin binding 1312467,24746669 Function
983 GO:0035173 IDA enables histone kinase activity 21871177 Function
983 GO:0097472 IDA enables cyclin-dependent protein kinase activity 1312467 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
983 GO:0006468 IDA involved_in protein phosphorylation 23509069,23574715,30723163 Process
983 GO:0006468 IMP involved_in protein phosphorylation 24746669 Process
983 GO:0010971 IMP involved_in positive regulation of G2/M transition of mitotic cell cycle 24746669 Process
983 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 11298763,19879842,25753036 Process
983 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 11298763,25753036 Process
983 GO:0018107 IMP involved_in peptidyl-threonine phosphorylation 27238018 Process
983 GO:0030855 IEP involved_in epithelial cell differentiation 21492153 Process
983 GO:0034501 IDA involved_in protein localization to kinetochore 18195732 Process
983 GO:0042752 IMP involved_in regulation of circadian rhythm 27238018 Process
983 GO:0043066 IDA involved_in negative regulation of apoptotic process 11069302 Process
983 GO:0062033 IDA involved_in positive regulation of mitotic sister chromatid segregation 26829474 Process
983 GO:1900182 IMP involved_in positive regulation of protein localization to nucleus 21871177 Process
983 GO:1902850 IDA involved_in microtubule cytoskeleton organization involved in mitosis 10791892 Process
983 GO:1905448 IMP involved_in positive regulation of mitochondrial ATP synthesis coupled electron transport 24746669 Process