Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:107527
  • Symbol:Il1rl2
  • Description:interleukin 1 receptor-like 2
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Gene ID Entry Entry Name Protein Name Type Information
107527 Q9ERS7 ILRL2_MOUSE Interleukin-1 receptor-like 2 (EC 3.2.2.6) (IL-36 receptor) (Interleukin-1 receptor-related protein 2) (IL-1Rrp2) (IL1R-rp2) DISRUPTION PHENOTYPE Complete protection from imiquimodum (IMQ)-induced skin pathology observed in wild-type mice, including hyperkeratosis, acanthosis, neutrophil recruitment, and expansion of IL-17-producing T-cells. {ECO:0000269|PubMed:23064362}.