Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:107751
  • Symbol:Prrxl1
  • Description:paired related homeobox protein-like 1
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
107751 Q8BYH0 DRGX_MOUSE Dorsal root ganglia homeobox protein (Dorsal root ganglion 11) (Homeobox protein DRG11) (Paired-related homeobox protein-like 1) DISRUPTION PHENOTYPE Defects in the projection pattern of nociceptive sensory neurons to the dorsal horn of the developing spinal cord leading to reduced sensitivity to painful stimuli. They die within 3 weeks of birth. Mice lacking Drgx exhibit reduced expression of Rgmb in dorsal root ganglion sensory neurons. {ECO:0000269|PubMed:11498051}.