Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:110147
  • Symbol:Ehmt2
  • Description:euchromatic histone lysine N-methyltransferase 2
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Gene ID Entry Entry Name Protein Name Type Information
110147 Q9Z148 EHMT2_MOUSE Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a) DISRUPTION PHENOTYPE Mice show a higher level of histone H3 with acetylated 'Lys-9' (H3K9ac) and/or methylated 'Lys-4' (H3K4me), display severe developmental defects and die within E9.5-E12.5 stages. {ECO:0000269|PubMed:12130538}.