| 11634 | Q9Z0E3 | AIRE_MOUSE | Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog) | DISRUPTION PHENOTYPE | Deficient mice show an altered thymic organization with altered morphology and location of mTECs (PubMed:19015306). They exhibit defective accumulation of thymic dendritic cells in the medullary region and generation of naturally ocurring T cells in the thymus (PubMed:21300913). {ECO:0000269|PubMed:19015306, ECO:0000269|PubMed:21300913}. |