| 12457 | O35710 | NOCT_MOUSE | Nocturnin (EC 3.1.3.108) (Carbon catabolite repression 4-like protein) | DISRUPTION PHENOTYPE | Mice exhibit metabolic defects including a resistance to diet-induced obesity, decreased fat storage, changes in lipid-related gene expression profiles in the liver, and altered glucose and insulin sensitivities. Exhibit a delayed early embryo development and at 12 weeks of age show enhanced skeletal mass and increased osteoblastogenesis. {ECO:0000269|PubMed:20498072, ECO:0000269|PubMed:21820310, ECO:0000269|PubMed:23449310}. |