| 12566 | P97377 | CDK2_MOUSE | Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) | DISRUPTION PHENOTYPE | Reduced body size and impaired neural progenitor cell proliferation. Sterility due to defective meiosis; no effect on mitotic cells. Premature translocation of CDK1 from the cytoplasm to the nucleus compensating CDK2 loss. Prolonged and impaired DNA repair activity upon DNA damage by gamma-irradiation. {ECO:0000269|PubMed:12923533, ECO:0000269|PubMed:14561402, ECO:0000269|PubMed:17942597}. |