Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:12593
  • Symbol:Cdyl
  • Description:chromodomain protein, Y chromosome-like
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Gene ID Entry Entry Name Protein Name Type Information
12593 Q9WTK2 CDYL_MOUSE Chromodomain Y-like protein (CDY-like) (Crotonyl-CoA hydratase) (EC 4.2.1.-) (Putative histone acetyltransferase Cdyl) (EC 2.3.1.48) DISRUPTION PHENOTYPE Mice show no overt differences in body weight, but males display a substantial decrease in the size and weight of the testis and show reduced fertility. Males show decreased epididymal sperm counts, sperm cell motility, and sperm velocity and a marked increase in cell apoptosis in the testis. {ECO:0000269|PubMed:28803779}.