| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 12703 | O35716 | SOCS1_MOUSE | Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) | DISRUPTION PHENOTYPE | Mice exhibit lymphocyte deficiency and degeneration of the liver parenchyma. Animals die within 3 weeks of age. Mutants show a much higher frequency of CD8 single positive thymocytes (PubMed:24880459). {ECO:0000269|PubMed:24880459, ECO:0000269|PubMed:9826711}. |
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