| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 13385 | Q62108 | DLG4_MOUSE | Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90) | DISRUPTION PHENOTYPE | Mice with a stop codon in the third PDZ domain have impaired spatial learning. NMDA-mediated synaptic plasticity is lost even though receptor levels and localization are unchanged. Long-term potentiation of synaptic transmission is enhanced due to minimal long-term depression. {ECO:0000269|PubMed:9853749}. |
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