Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:13733
  • Symbol:Adgre1
  • Description:adhesion G protein-coupled receptor E1
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Gene ID Entry Entry Name Protein Name Type Information
13733 Q61549 AGRE1_MOUSE Adhesion G protein-coupled receptor E1 (Cell surface glycoprotein F4/80) (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor) DISRUPTION PHENOTYPE Deficient mice fail to develop peripheral tolerance after inoculation with antigen because of a lack of efferent regulatory T-cell development. {ECO:0000269|PubMed:15883173}.