Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:13813
  • Symbol:Eomes
  • Description:eomesodermin
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Gene ID Entry Entry Name Protein Name Type Information
13813 O54839 EOMES_MOUSE Eomesodermin homolog (T-box brain protein 2) (T-brain-2) (TBR-2) DISRUPTION PHENOTYPE Embryonic lethal due to peri-implantation defects. Mutant embryos arrest soon after implantation and fail to form organized embryonic or extraembryonic structures. Conditional mutants, with expression abrogated in the inner cell mass of embryos from early implantation stages onward, display gastrulation defects. {ECO:0000269|PubMed:10716450}.