Gene ID | Entry | Entry Name | Protein Name | Type | Information | 14013 | P14404 | MECOM_MOUSE | Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein homolog) | DISRUPTION PHENOTYPE | Mice develop until 9.5 dpc but die before 11.5 dpc. At 10.5 dpc embryos display multiple malformations associated with hypocellularity and reduced body size. Required for neural, heart and paraxial mesenchyme. {ECO:0000269|PubMed:9256345}. |
---|