| 14063 | P55086 | PAR2_MOUSE | Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) | DISRUPTION PHENOTYPE | Delayed onset of inflammation. Reduced progression of osteoarthritis, infectious colitis, allergic dermatitis and experimental autoimmune encephalomyelitis. Upon induced allergic and toxic contact dermatitis ear swelling responses, plasma extravasation and leuocyte adherence are significantly attenuated. Upon ovalbumin (OA) sensitization and following challenge infiltration of eosinophils and increase of eotaxin content in bronchoalveolar lavage fluid are abrogated. {ECO:0000269|PubMed:11086091, ECO:0000269|PubMed:11859856, ECO:0000269|PubMed:14519665, ECO:0000269|PubMed:15879675, ECO:0000269|PubMed:15919826, ECO:0000269|PubMed:16476770, ECO:0000269|PubMed:20584806}. |