| 14633 | Q0VGT2 | GLI2_MOUSE | Zinc finger protein GLI2 (Tax helper protein) | DISRUPTION PHENOTYPE | Full embryonic lethality. Homozygous embryos are detected at the expected Mendelian rate up to about 18.5 dpc, but there are no live pups. Mutant embryos present important craniofacial defects, including defects of the medial portion of the frontal and parietal skull bones, absence of upper and/or lower incisors, often combined with a cleft palate. Besides, mutant embryos show defects in the ossification of skeletal bones and shortened limb bones. {ECO:0000269|PubMed:9006072}. |