| 15550 | Q64264 | 5HT1A_MOUSE | 5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (Serotonin receptor 1A) | DISRUPTION PHENOTYPE | Mutant mice display decreased exploratory behavior and increased fear-related behavior in anxiogenic environments. Mutant mice display altered monoamine metabolism in specific parts of the brain, especially in dorsal and medial raphe nuclei, thalamus and hypothalamus, leading to altered levels of 5-hydroxytryptamine, dopamine and their metabolites, as well as altered noradrenaline levels. {ECO:0000269|PubMed:11080193, ECO:0000269|PubMed:17543467, ECO:0000269|PubMed:9826725}. |