| 16569 | Q61771 | KIF3B_MOUSE | Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed] | DISRUPTION PHENOTYPE | Deficient mice do not survive beyond midgestation, exhibiting growth retardation, pericardial sac ballooning, and neural tube disorganization (PubMed:9865700). Kif3b +/- mice exhibit schizophrenia-like phenotypes, both behaviorally and histologically. Hippocampal neurons have altered spine morphology and synapse function, and at the cellular level, they display abnormal growth cone morphology (PubMed:31746486). {ECO:0000269|PubMed:31746486, ECO:0000269|PubMed:9865700}. |