Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:16666
  • Symbol:Krt16
  • Description:keratin 16
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
16666 Q9Z2K1 K1C16_MOUSE Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) DISRUPTION PHENOTYPE Mice were born alive at approximately Mendelian ratios but increased postnatal mortality is observed. Surviving mice show oral lesions as well as palmoplantar keratoderma-like hyperkeratotic calluses on front and hind paws, which impair the ability to walk. {ECO:0000269|PubMed:22336941}.