| 17286 | P32443 | MEOX2_MOUSE | Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2) | DISRUPTION PHENOTYPE | Mice display defective differentiation and morphogenesis of the limb muscles, characterized by an overall reduction in muscle mass and elimination of specific muscles (PubMed:10403250, PubMed:12925591). Embryos also display a cleft palate phenotype at 15.5 dpc (PubMed:16284941). Mice lacking Meox1 and Meox2 show extremely disrupted somite morphogenesis, patterning and differentiation (PubMed:12925591). They lack an axial skeleton and skeletal muscles are severely deficient (PubMed:12925591). {ECO:0000269|PubMed:10403250, ECO:0000269|PubMed:12925591, ECO:0000269|PubMed:16284941}. |