Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:17999
  • Symbol:Nedd4
  • Description:neural precursor cell expressed, developmentally down-regulated 4
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Gene ID Entry Entry Name Protein Name Type Information
17999 P46935 NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4) DISRUPTION PHENOTYPE Lethal during late gestation. Embryos show a retarded development and defects in vasculogenesis and angiogenesis. {ECO:0000269|PubMed:20159449}.