Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18092
  • Symbol:Nkx2-6
  • Description:NK2 homeobox 6
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
18092 P43688 NKX26_MOUSE Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F) DISRUPTION PHENOTYPE No visible phenotype; possibly due to the redundancy with NKX2-6. Mutant mice are viable and fertile. No obvious abnormalities in the caudal pharyngeal pouch derivatives (thymus, parathyroid glands, and thyroid gland), heart and gut. In NKX2-5 and NKX2-6 double mutants, the pharynx does not form properly and the development of the atrium is less advanced. {ECO:0000269|PubMed:10733590, ECO:0000269|PubMed:11390666}.