Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18291
  • Symbol:Nobox
  • Description:NOBOX oogenesis homeobox
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Gene ID Entry Entry Name Protein Name Type Information
18291 Q8VIH1 NOBOX_MOUSE Homeobox protein NOBOX (Homeodomain-containing protein OG-2) (Newborn ovary homeobox protein) (Oocyte-specific homeobox protein) DISRUPTION PHENOTYPE Male mice are fertile and show no obvious abnormality. Female mice lacking Nobox have normal gross anatomy and histology, but are infertile with atrophic ovaries that lack oocytes at 6 weeks of age. {ECO:0000269|PubMed:15326356}.