Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18387
  • Symbol:Oprk1
  • Description:opioid receptor, kappa 1
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Gene ID Entry Entry Name Protein Name Type Information
18387 P33534 OPRK_MOUSE Kappa-type opioid receptor (K-OR-1) (KOR-1) (MSL-1) DISRUPTION PHENOTYPE Mice are born at the expected Mendelian rate and show no obvious phenotype. Mutant mice do not display analgesia after treatment with the synthetic agonist U-50,488H. Unlike wild-type mice, they do not show reduced locomotion and increased salivation in response to the synthetic agonist U-50,488H. {ECO:0000269|PubMed:9463367}.