Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18441
  • Symbol:P2ry1
  • Description:purinergic receptor P2Y, G-protein coupled 1
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Gene ID Entry Entry Name Protein Name Type Information
18441 P49650 P2RY1_MOUSE P2Y purinoceptor 1 (P2Y1) (ADP receptor) (Purinergic receptor) DISRUPTION PHENOTYPE Platelets from mutant mice are defective in ADP-mediated platelet aggregation, leading to prolonged bleeding time. Otherwise, mice have no visible phenotype and do not display spontaneous bleeding. {ECO:0000269|PubMed:10606627}.