| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 18481 | Q61036 | PAK3_MOUSE | Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) (p21-activated kinase 3) (PAK-3) | DISRUPTION PHENOTYPE | Mice show significant abnormalities in synaptic plasticity as well as deficiencies in learning and memory. Pak1 and Pak3 double knockout mice display reduced brains characterized by simplified neuronal dendrites/axons and reduced synapse density. {ECO:0000269|PubMed:16014725, ECO:0000269|PubMed:21115725}. |
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