Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:18607
  • Symbol:Pdpk1
  • Description:3-phosphoinositide dependent protein kinase 1
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Gene ID Entry Entry Name Protein Name Type Information
18607 Q9Z2A0 PDPK1_MOUSE 3-phosphoinositide-dependent protein kinase 1 (mPDK1) (EC 2.7.11.1) DISRUPTION PHENOTYPE Mice show severe pancreatic hypoplasia at birth and ensuing hyperglycemia at postnatal stages and die of heart failure by 11 weeks of age. {ECO:0000269|PubMed:19429709, ECO:0000269|PubMed:19635472}.