18752 | P63318 | KPCG_MOUSE | Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13) | DISRUPTION PHENOTYPE | Mice exhibit impaired motor coordination due to the inability to eliminate multiple climbing fibers during innervation of Purkinje cells. 40% of Purkinje cells are still innervated by multiple climbing fibers. Exhibit food-anticipatory activity comparable to that of wild type mice but they do not reduce their late night activity or adapt their food intake amount to restricted feeding as efficiently as wild type mice. {ECO:0000269|PubMed:23185022, ECO:0000269|PubMed:8548809}. |