Gene ID | Entry | Entry Name | Protein Name | Type | Information | 19091 | P0C605 | KGP1_MOUSE | cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI) | DISRUPTION PHENOTYPE | Leads to premature death at approximately 6 weeks of age, presumably due to smooth muscle dysfunction. These mice show multiple defects including impaired smooth muscle relaxation, disturbed gastrointestinal motility and enhanced platelet adhesion. {ECO:0000269|PubMed:10209042, ECO:0000269|PubMed:9606187}. |
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