Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19250
  • Symbol:Ptpn14
  • Description:protein tyrosine phosphatase, non-receptor type 14
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Gene ID Entry Entry Name Protein Name Type Information
19250 Q62130 PTN14_MOUSE Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36) DISRUPTION PHENOTYPE PTPN14 deficient mice have swelling of the limbs or periorbital edema. These mice also show hyperplasia of lymphatic capillaries of the ears. There is no evidence of choanal atresia or any overtly dysmorphic features. {ECO:0000269|PubMed:20826270}.