19258 | Q9WU22 | PTN4_MOUSE | Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Testis-enriched protein tyrosine phosphatase) | DISRUPTION PHENOTYPE | PTPN4-deficient mice are born at normal Mendelian ratio with no apparent developmental or phenotypic defects. They display normal cytokine production and T-cell effector functions (PubMed:18614237). However, they show impairment in motor learning and cerebellar long-term depression (PubMed:17953619). {ECO:0000269|PubMed:17953619, ECO:0000269|PubMed:18614237}. |