Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19258
  • Symbol:Ptpn4
  • Description:protein tyrosine phosphatase, non-receptor type 4
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Gene ID Entry Entry Name Protein Name Type Information
19258 Q9WU22 PTN4_MOUSE Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Testis-enriched protein tyrosine phosphatase) DISRUPTION PHENOTYPE PTPN4-deficient mice are born at normal Mendelian ratio with no apparent developmental or phenotypic defects. They display normal cytokine production and T-cell effector functions (PubMed:18614237). However, they show impairment in motor learning and cerebellar long-term depression (PubMed:17953619). {ECO:0000269|PubMed:17953619, ECO:0000269|PubMed:18614237}.