Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:192652
  • Symbol:Wdr81
  • Description:WD repeat domain 81
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Gene ID Entry Entry Name Protein Name Type Information
192652 Q5ND34 WDR81_MOUSE WD repeat-containing protein 81 DISRUPTION PHENOTYPE Brain-specific, conditional knockout mice are born at the expected Mendelian frequency, but most of them die a few hours after birth. If they show no overt brain morphological abnormalities, a neuronal accumulation of SQSTM1 in foci is observed. {ECO:0000269|PubMed:28404643}.