| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 192656 | P58801 | RIPK2_MOUSE | Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (Receptor-interacting protein 2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2) | DISRUPTION PHENOTYPE | Mice show a lack of chemokine production induced by bacterial peptidoglycans. RIPK2 deficiency affects cellular signaling and cytokine responses triggered by NOD1 and NOD2 ligands, but not TLR ligands. {ECO:0000269|PubMed:17277144, ECO:0000269|PubMed:21469090}. |
|---|