Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19704
  • Symbol:Upf1
  • Description:UPF1 regulator of nonsense transcripts homolog (yeast)
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Gene ID Entry Entry Name Protein Name Type Information
19704 Q9EPU0 RENT1_MOUSE Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (mUpf1) DISRUPTION PHENOTYPE Embryos are viable in pre-implantation period, show complete loss of NMD but are resorbed shortly after implantation. {ECO:0000269|PubMed:11152657}.