Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19713
  • Symbol:Ret
  • Description:ret proto-oncogene
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Gene ID Entry Entry Name Protein Name Type Information
19713 P35546 RET_MOUSE Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] DISRUPTION PHENOTYPE Exclusive loss in nociceptors results in a reduction in nociceptor number and size with a reduced epidermal innervation, but increased sensitivity to cold and increased formalin-induced pain. {ECO:0000269|PubMed:20237269}.