Gene ID | Entry | Entry Name | Protein Name | Type | Information | 19877 | P70335 | ROCK1_MOUSE | Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) | DISRUPTION PHENOTYPE | Mice exhibit both EOB (eyes open at birth) and omphalocele phenotypes as a result of disorganization of actomyosin cables in the eyelid epithelium and defective actin assembly in the umbilical ring. {ECO:0000269|PubMed:15753128}. |
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