Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:19882
  • Symbol:Mst1r
  • Description:macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
19882 Q62190 RON_MOUSE Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (Stem cell-derived tyrosine kinase) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] DISRUPTION PHENOTYPE Mice show increased inflammation in an IFN-gamma-mediated delayed-type hypersensitivity reaction and increased susceptibility to lipopolysaccharide-induced endotoxic shock. {ECO:0000269|PubMed:9680329}.