Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:20459
  • Symbol:Ptk6
  • Description:PTK6 protein tyrosine kinase 6
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Gene ID Entry Entry Name Protein Name Type Information
20459 Q64434 PTK6_MOUSE Protein-tyrosine kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase) DISRUPTION PHENOTYPE Deficient mice have an increased cell turnover in the small intestine, which is accompanied by increased villus length and crypt depth and delayed enterocyte differentiation that is accompanied by increased PTK/AKT and WNT signaling. {ECO:0000269|PubMed:16782882}.