Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:20466
  • Symbol:Sin3a
  • Description:transcriptional regulator, SIN3A (yeast)
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Gene ID Entry Entry Name Protein Name Type Information
20466 Q60520 SIN3A_MOUSE Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) DISRUPTION PHENOTYPE SIN3A knockdown causes a significant decrease in the amount of cortical progenitors in the proliferative zone at the peak of neurogenesis, and results in altered neuronal identity and aberrant corticocortical projections. {ECO:0000269|PubMed:27399968}.