| 208777 | Q70E20 | SNED1_MOUSE | Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein) | DISRUPTION PHENOTYPE | Early neonatal lethality, possibly due to impaired nasal respiration caused by asymmetric and occluded nasal cavities (PubMed:33012048). In addition to nasal cavity occlusion, mice display growth defects and craniofacial malformations (PubMed:33012048). Mice with a specific deletion in neural crest-cells survive, but display growth defects and craniofacial malformations partly phenocopying the effect of the global knockout mice (PubMed:33012048). {ECO:0000269|PubMed:33012048}. |