| 208922 | Q7TN99 | CPEB3_MOUSE | Cytoplasmic polyadenylation element-binding protein 3 (CPE-BP3) (CPE-binding protein 3) (mCPEB-3) | DISRUPTION PHENOTYPE | Enhanced thermal sensitivity and increased levels of Trpv1 in lumbar sciatic nerves and spinal cord (PubMed:26915043). Elevated short-term fear response, enhanced long-term spatial memory, dendritic spine enlargement and elevated levels of Dlg4/Psd95, Gria1 and NMDA receptor subunits Grin1, Grin2a and Grin2b (PubMed:26074071). Conditional knockout in the adult forebrain results in viable mice with no gross neurological defects which display normal locomotor, exploratory and anxiety behaviors but have impaired long-term memory, impaired long-term synaptic plasticity and increased levels of Gria1 and Gria2 (PubMed:26074003). {ECO:0000269|PubMed:26074003, ECO:0000269|PubMed:26074071, ECO:0000269|PubMed:26915043}. |