| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 209462 | Q3U0D9 | HACE1_MOUSE | E3 ubiquitin-protein ligase HACE1 (EC 2.3.2.26) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1) (HECT-type E3 ubiquitin transferase HACE1) | DISRUPTION PHENOTYPE | Mice develop spontaneous, late-onset cancer. Moreover, tumor incidence in mice heterozygous for a p53/Tp53 mutation in higher in a Hace1-deficient background. {ECO:0000269|PubMed:17694067}. |
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