212712 | Q8VI24 | SATB2_MOUSE | DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2) | DISRUPTION PHENOTYPE | Malformations in 2 of the major axonal tracts interconnecting the cortical hemispheres: the corpus callosum (c.c) and the anterior commissure (a.c). Misrouted afferent and efferent cortical axon connections. Impaired migration of upper-layer neurons. Ectopic expression of Ctip2. Craniofacial abnormalities and defects in osteoblast differentiation and function. {ECO:0000269|PubMed:16751105, ECO:0000269|PubMed:18255030, ECO:0000269|PubMed:18255031}. |