21375 | Q64336 | TBR1_MOUSE | T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56) | DISRUPTION PHENOTYPE | Homozygous mutant mice do not nurse and die between postnatal days 1 and 3 (PubMed:9883721, PubMed:11239428). Brains are smaller than those of heterozygous or wild-type littermates, olfactory bulbs are small and olfactory bulb projection neurons are absent (PubMed:9883721). Mutant mice show severe defects of cortical development (PubMed:11239428). {ECO:0000269|PubMed:11239428, ECO:0000269|PubMed:9883721}. |