Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:215798
  • Symbol:Adgrg6
  • Description:adhesion G protein-coupled receptor G6
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Gene ID Entry Entry Name Protein Name Type Information
215798 Q6F3F9 AGRG6_MOUSE Adhesion G-protein coupled receptor G6 (Developmentally regulated G-protein-coupled receptor) (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)] DISRUPTION PHENOTYPE Deficient mice die during organogenesis. Mutant embryos show signs of myocardial wall thinning, hypotrabeculation, defective mitochondrial and circulatory failure. {ECO:0000269|PubMed:21124978, ECO:0000269|PubMed:24082093}.