Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:21930
  • Symbol:Tnfaip6
  • Description:tumor necrosis factor alpha induced protein 6
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Gene ID Entry Entry Name Protein Name Type Information
21930 O08859 TSG6_MOUSE Tumor necrosis factor-inducible gene 6 protein (TNF-stimulated gene 6 protein) (TSG-6) (Tumor necrosis factor alpha-induced protein 6) (TNF alpha-induced protein 6) DISRUPTION PHENOTYPE Mutant female mice are infertile due to impaired cumulus oophorus expansion upon gonadotropin surge (PubMed:12668637). Mutant mice have twice the bone mass of wild-type littermates. They show increased trabecular number and trabecular thickness (PubMed:18586671). {ECO:0000269|PubMed:12668637, ECO:0000269|PubMed:18586671}.