Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:22352
  • Symbol:Vim
  • Description:vimentin
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
22352 P20152 VIME_MOUSE Vimentin DISRUPTION PHENOTYPE Morphological change from tubular conformation to circular conformation of beaded filament structures in retinal lens epithelium, potentially due to loss of contacts with surrounding intermediate filaments (PubMed:27559293). BFSP2 and VIM double knockout mice show a complete loss of cytoplasmic cytoskeleton in retinal lens fiber cells (PubMed:15037121). {ECO:0000269|PubMed:15037121, ECO:0000269|PubMed:27559293}.