| 22359 | P98156 | VLDLR_MOUSE | Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) | DISRUPTION PHENOTYPE | Deletion mutant mice show an increase in serum triglycerides under a high fat diet, suggesting a role in extrahepatic triglyceride uptake (PubMed:11108739). In addition, these mice show a reduced high fat diet-induced inflammation and endoplasmic reticulum (ER) stress in adipose tissue in conjunction with reduced macrophage infiltration (PubMed:24293365). {ECO:0000269|PubMed:11108739, ECO:0000269|PubMed:24293365}. |