Gene ID | Entry | Entry Name | Protein Name | Type | Information | 225865 | Q91ZR5 | CTSR1_MOUSE | Cation channel sperm-associated protein 1 (CatSper1) | DISRUPTION PHENOTYPE | Mice are normal but males are sterile. Male sterility is due to defects in sperm motility unability to fertilize intact eggs. In mice lacking Catsper1, sperm lacks CatSper2 protein, while in mice lacking CatSper1, sperm lacks CatSper1 protein, suggesting that stable expression of CatSper1 protein requires CatSper2 and vice versa. {ECO:0000269|PubMed:11595941}. |
---|