| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 22637 | P43404 | ZAP70_MOUSE | Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase) | DISRUPTION PHENOTYPE | Mice lack both CD4 and CD8 positive mature T-lymphocytes. Displays a complete block in B-Cell development at the pro-B cell stage in the absence of both SYK and ZAP70. {ECO:0000269|PubMed:12705855, ECO:0000269|PubMed:7630421}. |
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